Endocrine Abstracts

We studied 5 female patients, aged 54–79 years old (mean 70.6 years), on PPI therapy for 2–13 years (mean 8.2 years), who were symptomatic from chronic and sometimes severe hypomagnesaemia (lowest readings 0.36, 0.29, & <0.21 mmol/l in 3 patients) for 7–45 months (mean 29.2 months). Oral magnesium (Mg) supplements were either poorly tolerated or ineffective; and repeated magnesium sulphate infusions (total doses per patient 120–1200 mmol Mg, mean 44...

Introduction: TNDM due to genetic aberrations at 6q24 is the commonest cause of diabetes presenting within the first week of life. TNDM predisposes to diabetes mellitus in later life. We report on the clinical presentation of the largest worldwide cohort of 6q24 TNDM cases.Results: 164 cases were analysed. The mean age of presentation was 8 days with a mode of 1 day and maximum age of presentation of 90 days. On average, babies recovered by 4.5 months wi...